The Topical Niacin Skin Flush Test in First Episode Psychosis

Exclusion Criteria

• •known allergy to study compound (methyl nicotinate, vitamin B3, niacin)
• •skin conditions (e.g., dermatitis, psoriasis, eczema)
• •diagnosis or treatment for medical conditions that may affect normal vascular tone (e.g., diabetes, vasculitis, chronic hypertension, etc.)
• •Use of anti-inflammatory, antibiotic, or antihistamine medications within one month prior to study entry
• •Use of supplements like Omega 3 fatty acids within 3 months prior to study entry
• •Use of vitamin or nutritional supplement containing a dose of niacin/nicotinic acid above 50 mg/day at study entry