Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Children's Hospital Los Angeles
With
The Leukemia and Lymphoma Society
Age
10–29
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
GROUP A: Patients with newly diagnosed ALL
Are greater than or equal to 10 years of age and less than or equal to 21 years of age at diagnosis of ALL
Have a new diagnosis of untreated ALL classified as "high risk" per NCI criteria (due to being greater than 10 years of age)
Are beginning treatment with a Children's Cancer Group/Children's Oncology Group "high risk" protocol with a 4-drug induction including steroids
Are not pregnant
GROUP B: Early survivors of ALL
Were treated for ALL and remain in first CR1 (complete remission)
Were equal to or greater than 10 years of age and less than or equal to 21 years of age at diagnosis of ALL
Have completed treatment on or as per a Children's Cancer Group/Children's Oncology Group "high risk" protocol between 12 and 48 months prior to enrollment in this study (consisting of a plan for a 4-drug induction including steroids in Induction, Delayed Intensification, and steroid pulses in Maintenance. Steroids are allowed to have been discontinued due to toxicity).
Are not pregnant
GROUP C: Siblings of Group A
Are either a full-sibling or a half-sibling of a patient in Group A
Are living at the same residence as the sibling/half-sibling from Group A
Are greater than or equal to 10 years of age and less than or equal to 21 years of age at the time of study entry, and within 3 years of the age diagnosis of ALL in the sibling/half-sibling from Group A
Are on the same Vitamin D supplementation regimen (if any) as the sibling from Group A at the time of his or her diagnosis
You may not be if
Have a diagnosis of Down syndrome (Trisomy 21) or any genetic disease associated with abnormal bone development
Are undergoing treatment with other medicines that affect bones including chronic use of of steroids, bisphosphonate therapy, or Vitamin D at average dose greater than 400 international units (IU)/day
Have an underlying diseases altering body structure (i.e. missing a limb, severe dysmorphism) or severely affecting mobility (i.e. total or hemiparesis)
Have a history of chemotherapy or radiation for other cancers
Cannot complete the radiology exams/radiology exams uninterpretable (i.e. people with a hip replacement or prosthesis)
Clareo Health | Nutrition and Body Composition in Acute Lymphoblastic Leukemia
