Prediction of Progression of Coronary Artery Disease (CAD) Using Vascular Profiling of Shear Stress and Wall Morphology

Exclusion Criteria

• •Heart failure, defined as NYHA Class III or IV
• •Unstable clinical status (ongoing anginal pain or hemodynamic or electrical instability)
• •Left main disease or three vessel disease
• •In the opinion of the investigator, significant coronary calcification precluding protocol evaluations
• •Investigator determination of renal failure of sufficient severity such that additional contrast material is contraindicated
• •Clinically significant valvular heart disease
• •Investigator opinion of life expectancy \< 12 months
• •Subject is currently participating in an investigational drug or device study that has not completed the primary endpoint or that clinically interferes with the current study endpoints. (Note: Studies requiring extended follow-up for products that were investigational, but have since become commercially available, are not considered investigational studies)
• •Women who are pregnant, seeking to become pregnant or suspect they are pregnant.