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COMPLETEDNCT01301235

Defining 31Phosphorous Magnetic Resonance Spectroscopy Characteristics in Patients With Mitochondrial Myopathy

This is a developmental protocol to determine the MRI based 31P-MRS changes seen in subjects with mitochondrial myopathy using our dynamic exercise protocol and to identify the ideal variable(s) to re...

Lead sponsor: Massachusetts General Hospital•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Massachusetts General Hospital

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Men and women ≥ age 18 years old with primary mitochondrial myopathy
•2. Known alteration in electron transport chain activity (\<25 % activity of ETC) or known mutations in mitochondrial gene.

Exclusion Criteria

•Failure based on standard clinical MRI Screening form - the form is intended to establish the safety of subjects participating in the MRI scan without divulging any confidentiality information -

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 30, 2012Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment8

Start dateFeb 2011

Last updatedApr 30, 2012

Condition

Mitochondrial Disease

Locations shown

Massachusetts General Hospital

Boston, Massachusetts

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 30, 2012Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions