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A Study to Assess the Antibody Response of Healthy Chinese Children Who Have Been Vaccinated Previously With 4-doses of Prevenar (a Pneumococcal Vaccine) as Babies and Toddlers | Clinical Trials | Clareo Health

COMPLETEDPHASE4

A Study to Assess the Antibody Response of Healthy Chinese Children Who Have Been Vaccinated Previously With 4-doses of Prevenar (a Pneumococcal Vaccine) as Babies and Toddlers

A Phase 4, Open-label Study to Evaluate Persistence of the Antibody Response Elicited by Prevenar in Healthy Children in China Who Have Been Previously Immunized With a 4-dose Series of a Pneumococcal Conjugate Vaccine During Infancy in Study 0887x-101518

NCT01298544•Pfizer

View on ClinicalTrials.gov

Summary

In 2005, Wyeth conducted study 0887X-101518 (NCT00488826) in which Chinese infants received either Prevenar alone (Group 1), Prevenar given with a Diphtheria, Tetanus and acellular Pertussis (DTaP) vaccine (Group 2) or DTaP alone (Group 3). This follow up study (at least 3 years after the last vaccination) will assess the antibody concentrations in children who previously completed Wyeth study 0887X-101518.

Eligibility

Age

4 - 5 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Male or female subjects who participated in and completed Wyeth study 0887X 101518.
•Healthy subject as determined by medical history, physical examination, and judgment of the investigator.

Exclusion Criteria

•Vaccination with any licensed or investigational pneumococcal vaccine since completion of Wyeth study 0887X 101518.
•History of culture proven invasive disease caused by S pneumoniae since the completion of Wyeth study 0887X 101518.
•Known or suspected immune deficiency or suppression since participation in Wyeth study 0887X 101518.

Locations (10)

Chengxiang Town Hospital

Longan County, Guangxi, China

Longan County CDC

Longan County, Guangxi, China

Nanyu Town Hospital

Longan County, Guangxi, China

Yanjiang Town Hospital

Longan County, Guangxi, China

Natong Town Hospital

Longan County, Guangxi, China

Qiaojian Town Hospital

Longan County, Guangxi, China

Gutan Village Hospital

Longan County, Guangxi, China

Dingdang Town Hospital

Longan County, Guangxi, China

Yangwan Hospital

Longan County, Guangxi, China

GuangXi Center for Disease Prevention and Control

Nanning, Guangxi, China

Key Dates

Start Date

November 1, 2010

Primary Completion Date

March 1, 2011

Completion Date

March 1, 2011

Last Updated

December 19, 2018

Enrollment

335

ACTUAL participants

Conditions

Pneumococcal Disease

Interventions

Blood draw

PROCEDURE

Carriage to Assess Protection of New Pneumococcal Vaccines - PCV15

NCT06731374

Pneumococcal DiseasePneumococcal Carriage

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RECRUITINGPHASE3

A Clinical Trial to Evaluate the Immunogenicity and Safety of the 23-valent Pneumococcal Polysaccharide Vaccine in Healthy People

NCT06044077

Pneumococcal Disease

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ACTIVE_NOT_RECRUITING

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 19, 2018Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Study to Assess the Antibody Response of Healthy Chinese Children Who Have Been Vaccinated Previously With 4-doses of Prevenar (a Pneumococcal Vaccine) as Babies and Toddlers

Inclusion Criteria

Exclusion Criteria

Carriage to Assess Protection of New Pneumococcal Vaccines - PCV15

A Clinical Trial to Evaluate the Immunogenicity and Safety of the 23-valent Pneumococcal Polysaccharide Vaccine in Healthy People

Phase 2 Trial to Evaluate Safety and Immunogenicity of Inventprise's (IVT) 25-valent Pneumococcal Conjugate Vaccine (IVT PCV-25) in Healthy Infants

Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 50 Years of Age or Older (V116-010, STRIDE-10)

A Study to Learn About How Safe and Effective is 20vPnC and 13vPnC Vaccines in Chinese Adults

20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Pneumococcal Vaccine-Naïve Adults 60 Years of Age and Older in Japan, Korea, and Taiwan