Rapid Evaluation of Acute Kidney Injury With NGAL in Acutely Ill Patients in the ICU

The study will be conducted in two phases. Phase One is specimen acquisition and subject diagnosis adjudication. Phase Two is biomarker testing. Phase One Approximately 850 adults admitted to general ICUs will be enrolled within 12 hours of receipt of ICU admission orders. Study specific whole blood and urine specimens will be collected. There is an Adjudication Committee for this study. This committee is comprised of qualified, board-certified nephrologists. Phase Two During Phase Two, the plasma specimens will be divided amongst three clinical sites representative of the intended end users of this assay, and tested under a separate testing protocol.