Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Bordeaux
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 18 years old and ≤ 75 years old
Chronic Obstructive Pulmonary Disease with FEVs/VC \< 70% (\*)
Respiratory pulmonary hypertension with mean pulmonary arterial pressure ≥ 20 mmHg (\*) related to normal pulmonary capillar pressure assessed by catheterization of the right side of the heart (pulmonary capillary wedge pressure ≤12mmHg)
PO2 ≤ 70 mmHg assessed by arterial gasometry at ease
If oxygenotherapy then oxygenotherapy more than 6 months before pre-screening
Written informed consent
(\*) Criteria assessed from last health check or the last exams for COPD diagnosis
You may not be if
clinical instability and/or respiratory exacerbation dangerous for catheterization
Pregnancy (ßHCG \> 20 UI /l) or breastfeeding on going
General corticotherapy \> 0,5 mg/kg/day prednisolon equivalent
Hepatic insufficiency (TP \< 50%) or renal insufficiency (creatininemia \> 130 µmol/l) or diabetes mellitus type I or II (treated by oral antidiabetic or insulin)
Left-heart failure (coronary heart disease and/or left valvulopathy)
High level of prostatic specific antigen (PSA) (\> 7ng/ml)
Cancer antecedent or treatment on going
Clareo Health | Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults (DHEA-HTAP)
