Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism

Exclusion Criteria

• •Use of an injectable, oral, topical, or subcutaneous pelleted testosterone within 6 months prior to study
• •Use of spironolactone, cimetidine, Clomid, 5α-reductase inhibitors, hCG, androgen, estrogen, anabolic steroid, DHEA, or herbal hormone products during the study
• •Use of Clomid in the past year
• •Uncontrolled hypertension or diabetes mellitus based on the Investigator's assessment at baseline. Subjects treated for Type II diabetes but exhibiting glycemic control will be allowed into the study
• •A hematocrit \>50% or a hemoglobin \>17 g/dL
• •Clinically significant abnormal findings on screening examination
• •Use of an investigational drug or product, or participation in a drug or medical device research study within 30 days prior to receiving study medication
• •Known hypersensitivity to Clomid
• •Symptomatic cataracts (nuclear sclerosis cataract or cortical cataract grade \> 2 based on 0-4 scale or any trace of posterior subcapsular cataract)
• •Any condition which in the opinion of the investigator would interfere with the participant's ability to provide informed consent, comply with study instructions, possibly confound interpretation of study results, or endanger the participant if he took part in the study
• •Irreversibly infertile or compromised fertility (cryptorchism, Kallman Syndrome, primary hypogonadism, vasectomy, or tumors of the pituitary)
• •Current or history of breast cancer
• •Current or history of prostate cancer or a suspicion of prostate disease unless ruled out by prostate biopsy, or a PSA\>3.6
• •Presence or history of hyperprolactinemia with or without a tumor
• •Chronic use of medications use such as glucocorticoids
• •Subjects with cystic fibrosis (mutation of the CFTR gene)
• •Subjects unable to provide a semen sample in the clinic
• •Subject has a BMI \>36 kg/m2