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COMPLETEDPhase 4NCT01265420

Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb

This study will evaluate the efficacy and safety of clostridial collagenase injections for treatment of Dupuytren's contracture of the thumb and first web space. The investigators hypothesis is that c...

Lead sponsor: Indiana Hand to Shoulder Center•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Indiana Hand to Shoulder Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Adult subjects (\> 18 years) of either gender with an MP and/or IP joint contracture and a palpable cord of \> 20 degrees of the thumb
•First web space contracture with a palpable cord due to Dupuytren's contracture

Exclusion Criteria

•Prior surgical, percutaneous needle aponeurotomy or Xiaflex treatment for Dupuytren's contracture of the same thumb.
•Any subject using anti-coagulant therapy other than low dose aspirin (up to 150mg/day).
•Any subject in the opinion of the MD investigators with chronic, severe or terminal medical illness which would make them unsuitable for study participation.
•Any subject with known allergy to Xiaflex (Clostridial collagenase).
•Pregnant or nursing female
•Any subject who cannot conform to the study visit schedule

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 30, 2015Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment7

Start dateDec 2010

Last updatedApr 30, 2015

Condition

Dupuytren's Contracture

Locations shown

Indiana Hand to Shoulder Center

Indianaplis, Indiana

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 30, 2015Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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