Loading clinical trials...

TERMINATED

Cardiometabolic Risk of Shiftwork

Cardiometabolic Risk of ShiftWork: Sleep Loss vs.Circadian Disruption

NCT01264913•University of Chicago

Summary

The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than day workers, and that the accumulated sleep debt and the degree of circadian misalignment both predict their elevated cardio-metabolic risk.

Eligibility

Age

18 - 50 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Day workers and shift workers at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center who have maintained their work schedule (at least 30 hours/week) for at least 6 months.
•Individuals who have been shift workers for less than 10 years; body mass index \<40 kg/m2;
•No major illness
•No history of psychiatric, endocrine, cardiac or sleep disorders
•Those with hypertension or dyslipidemia will be included if these conditions are controlled by a stable treatment.
•Women taking oral contraceptive or hormonal replacement therapy will be included only if they plan to stay on a stable regimen throughout the study.
•Age must be between 18 and 50 years

Exclusion Criteria

•Individuals who have worked at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center in their current position for less than 6 months.
•Individuals who have been shift workers for more than 10 years
•BMI\>40 kg/m2
•Individuals with a major illness (e.g. diabetes, sleep disorder)

Locations (1)

The University of Chicago

Chicago, Illinois, United States

Key Dates

Start Date

August 1, 2009

Primary Completion Date

March 1, 2015

Completion Date

March 1, 2015

Last Updated

October 3, 2016

Enrollment

ACTUAL participants

Conditions

Sleep DeprivationCircadian DysregulationShift-Work Sleep Disorder

Interventions

sleep extension & circadian alignment

BEHAVIORAL

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

NCT06070194

Sleep Deprivation

View study

RECRUITINGNA

Nighttime Synchrony of Your Nutrition and Circadian Health

NCT07329283

SleepMetabolism Changes+9 more

View study

RECRUITING

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 3, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Cardiometabolic Risk of Shiftwork

Inclusion Criteria

Exclusion Criteria

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

Nighttime Synchrony of Your Nutrition and Circadian Health

Effects of Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD) on Memory and Cognitive Function in Adults With Sleep Deprivation: A Proof-of-Concept Study

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

Immune Status After Being on Call for 24 Hrs

Menstrual-phase-dependent Differences in Response to Sleep Loss