Lead Sponsor

Shire

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•1. Adult subjects, 18 years of age and over, who understand the risks and benefits of participation and have provided written informed consent for the study.
•2. Subjects who are experiencing a first event or first recurrence of clostridium difficile (CDI) within the last 28 days and have been successfully treated with an antibiotic for CDI.
•3. Subjects who are medically stable.
•4. Subjects who are willing and able to comply with the study procedures and visit schedules outlined.
•5. If female be post-menopausal, surgically sterile or agree to follow an acceptable method of birth control.

•1. Subjects who have had more than 2 episodes of CDI within the last 6 months.
•2. Subjects who have been diagnosed with Inflammatory Bowel Disease,active Irritable Bowel Syndrome, celiac disease, active gastroparesis, toxic megacolon.
•3. GI surgery within 6 weeks before the day of randomization
•4. Have known immunodeficiency disorder, such as HIV Infection
•5. Pregnant or breast feeding females.
•6. Concurrent acute life-threatening diseases.
•7. Inability to tolerate oral liquids.
•8. Have an absolute neutrophil count \< 1000/mm3 at screening