1. Patients with body mass index (BMI) less than 18.5 kg/m2 or more than 35 kg/m2

2. History of alcohol or substance abuse within the last six months.

3. History of seizures or use of anticonvulsant medication.

4. Any psychiatric condition that requires medication or may interfere with study participation.

5. Pre-existing cardiovascular disorders including severe hypertension, heart failure, myocardial infraction, etc.

6. Significant respiratory, hepatic, gastrointestinal, renal, hematological or oncologic disorder

7. Diagnosis of glaucoma, hyperthyroidism, pheochromocytoma

8. Diagnosis or family history of Tourette's syndrome

9. Pre-existing cerebrovascular disorders such as cerebral aneurysm, vascular abnormalities including vasculitis or stroke

Efficacy and Safety Study of Methylphenidate Hydrochloride Extended Release in Adults With Childhood-onset Attention Deficit/Hyperactivity Disorder (ADHD)