Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Northwestern University
With
Robert H. Lurie Cancer Center
OBJECTIVES: I. To determine if weight loss in patients undergoing Roux en Y gastric bypass procedures has any effect on breast density as measured by mammography and breast MRI. OUTLINE: GROUP I: Participants undergo mammography and MRI at baseline and 1 year. Participants also undergo gastric bypass surgery. GROUP II: Participants undergo mammography and MRI at baseline and 1 year. After completion of study treatment, patients are followed up at 1 year.
Age
30–50
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Women eligible for gastric bypass surgery
Pre-menopausal women
All women will have signed an informed consent form prior to participating in study procedures
You may not be if
Women with a history of breast cancer
Women currently taking exogenous hormone replacement therapy
Women currently taking a SERM
Women currently taking an aromatase inhibitor
Pregnant or lactating women
Women who have been pregnant or lactating in the past 2 years
Women who have metallic or other surgical implants
All subjects will have a determination of their estimated glomerular filtration rate (eGFR) within 24 hours of undergoing any study where gadolinium based contrast agents will be administered
Subjects should not have a known history of recent onset acute renal dysfunction
Subjects with a history of stable chronic renal dysfunction may participate in studies using GBCA based on their eGFR, as outlined below
Subjects should not have severe liver dysfunction, particularly when associated with kidney disease
Subjects should receive GBCAs in the perioperative period (i.e. within 4 weeks) after renal or liver transplantation
