Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Peking University Cancer Hospital & Institute
1. The patiets with malignant pleural effusion are randomizned to be treated with cytokins(inteleukin 2) or dendritic cells(DC) plus cytokine induced killer cells(CIK) locally.
2. Malignant pleural effusion from metastatic breast cancer patient is obtained through thoracentesis and is centrifugalized to enrich cancer cells before the therapy.
3. The enriched cancer cells are flash frozen and stored at -80℃ until processing.
4. The gene expression in pleural effusion is detected by microarray to screen gene markers that are differently expressed between groups .
5. Statistical analysis is performed using unsupervised hierarchical cluster.
Age
18–75
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Patients should be histologically confirmed with metastatic breast cancer and malignant pleural effusion
an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2;
At least one measurable lesion;
Normal cardiac, hepatic, renal and bone marrow functions;
Life expectancy ≥3 months;
Discontinuity of previous chemotherapy for a minimum of 4 weeks.
Not receive chemotherapy in pleural cavity
You may not be if
previous history of other malignancies;
previous surgery history on the needle biopsy organ;
Serious or uncontrolled concurrent medical illness.
Clareo Health | Gene Expression Profiling of Breast Cancer Cells Predict the Response of Malignant Pleural Effusion
