Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure

Inclusion Criteria

• •Males and females 65 years of age with cardiovascular disease who are referred for a coronary catheterization procedure with or without PCI.
• •The subject has at least one of the following comorbidities:
• •1\) Chronic renal insufficiency, (eGFR \<60 but 15 mL/min/1.73 m2 according to the MDRD equation) as measured within 2 weeks or at the screening visit;
• •2\) DM diagnosed greater than 6 months prior to study entry and which requires either insulin or anti-hyperglycemic drug therapy;
• •3\) CHF (NYHA) class III or greater measured within 2 weeks of enrollment or at the screening visit.