Previous treatment with chemotherapy.

Clinical signs of brain metastases.

Severe cardiac insufficiency (NYHA III or IV) with uncontrolled and/or unstable cardiac or coronary artery disease.

Severe active infections such as HIV or hepatitis B or Hepatitis C.

Medication for severe intercurrent disease which might affect immunocompetence (e.g. immunosuppressants, systemic corticosteroids).

Pregnancy, breast-feeding or absence of adequate contraception for fertile patients.

Simultaneously participation in other clinical studies.

Any reason why, in the opinion of the investigator, the patient should not participate.

Trial With Telomerase Peptide Vaccine In Combination With Temozolomide in Patients With Advanced Malignant Melanoma