Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Stanford University
Patients are randomized to receive aminophylline or placebo for 72 hours, in a blinded fashion. Serum theophylline levels monitor for safety of aminophylline dose. Goal theophylline levels is 5-7 mcg/ml. Laboratory results will be faxed directly to the pharmacy who will adjust subsequent aminophylline dosing to maintain appropriate theophylline levels. Urine output and serum creatinine levels will be monitored to assess acute kidney injury. Serum Neutrophil Gelatinase Associated Lipocalin (NGAL) levels will also be monitored.
Age
0–18
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Less than 18 years old, undergoing cardiac surgery with bypass
neonates must be at least 36 weeks gestational age
You may not be if
History of arrythmia or seizure, on extracorporeal membrane oxygenation (ECMO) support, already taking aminophylline/theophylline, liver failure, sepsis, on renal replacement therapy
Clareo Health | Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery
