A recipient must meet the following requirement to enroll into the study:

Requires a single or bilateral lung transplant and is listed for lung transplant at UNC.

Male or Female, 18 years of age or older.

Subject or Subject's Representative provides a legally effective informed consent.

Recipient does not have HIV, active Hepatitis or is colonized with Burkholderia cepacia.

Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability