Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Oklahoma
With
Oklahoma Center for the Advancement of Science and Technology
Milton S. Hershey Medical Center
Age
60–100
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
women 60 years of age and older having a positive history of intermittent claudication assessed by the San Diego Claudication Questionnaire
exercise limited by intermittent claudication during a screening treadmill test using the Gardner protocol
an ankle/brachial index (ABI) \< 0.90 at rest or \< 0.73 immediately following the treadmill exercise test
at least one year past menopause
You may not be if
absence of PAD (peripheral artery disease)
asymptomatic PAD (Fontaine stage I)
rest pain due to PAD (Fontaine stage III)
tissue loss due to PAD (Fontaine stage IV)
medical conditions that are contraindicative for exercise according to the American College of Sports Medicine (e.g., acute myocardial infarction, unstable angina, etc.)
use of medications indicated for the treatment of intermittent claudication (cilostazol and pentoxifylline) initiated within three months prior to investigation)
cognitive dysfunction (mini-mental state examination score \< 24)
active cancer, renal disease, or liver disease
a calf skin fold measurement \> 50 mm, because of potential interference with the light path of the near-infrared spectroscopy probe from penetrating the subcutaneous tissue
pulse arterial oxygen saturation of the index finger \< 95% because of the potential deleterious effect on calf muscle StO2 from poor pulmonary gas exchange
