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Weaning And Variability Evaluation | Clinical Trials | Clareo Health

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COMPLETEDNCT01237886

Weaning And Variability Evaluation

Knowing when to liberate patients from mechanical ventilation (i.e. removal of breathing or endotracheal tube or extubation) is critically important, as both prolonged ventilation and failed extubatio...

Lead sponsor: Ottawa Hospital Research Institute•7 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Ottawa Hospital Research Institute

Collaborators

Canadian Institutes of Health Research (CIHR)

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Invasive mechanical ventilation for \>48 hours,
•patient is ready for SBTs for assessment for extubation,
•has a normal sinus rhythm at time of SBT (no pacemaker),
•is tolerating pressure support ventilation ≤14 cm H2O (SpO2 ≥ 90% with FiO2 ≤ 40% and PEEP ≤ 10 cm H2O),
•hemodynamically stable (low or no vasopressors), stable neurological status (no deterioration in GCS during prior 24 hours \& ICP \< 20),
•intact airway reflexes (cough \& gag).

Exclusion Criteria

•Order not to re-intubate,
•anticipated withdrawal of life support,
•known or suspected severe weakness (myopathy, neuropathy or quadriplegia),
•tracheostomy,
•and prior extubation during ICU stay.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 7, 2017Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment660

Start dateNov 2009

Last updatedJul 7, 2017

Condition

Mechanically Ventilated Patients Extubation

Locations shown

The University of Michigan Medical Center

Ann Arbor, Michigan

Billings Clinic

Billings, Montana

Dartmouth Hitchcock Memorial Hospital

Lebanon, New Hampshire

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 7, 2017Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions