Lead Sponsor

Centre Muraz

Collaborators

Age

0 - No limit years

Sex

ALL

Healthy Volunteers

No

•Males and Females aged 6 months and above.
•Body weight of 5 Kg and above.
•RDT positive test.
•Fever (axillary temperature at ≥ 37.5°C) or history of fever in the previous 24 hours.
•Signed (or thumb-printed whenever patients are illiterate) informed consent.
•Patients' willingness and ability to comply with the study protocol for the duration of the study.

•Participation in any other investigational drug study (antimalarial or others) during the previous 30 days.
•Known hypersensitivity to the study drugs.
•Severe malaria.
•Danger signs: not able to drink or breast-feed, vomiting (\> twice in 24hours), recent history of convulsions (\>1 in 24h), unconscious state, unable to sit or stand.
•Known intercurrent illness or any condition (cardiac, renal, hepatic diseases) which in the judgement of the investigator would place the subject at undue risk or interfere with the results of the study.
•Severe malnutrition (defined as weight for height \<70% of the median NCHS/WHO reference).