Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Chinese University of Hong Kong
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age over 18 with informed consent.
Fulfill the revised American College of Rheumatology criteria for SLE
Biopsy-proven class III, IV, or V lupus nephritis within the past 24 months.
Could not achieve complete remission after at least 4 months of conventional therapy (oral steroid plus cyclosphosphamide or mycophenolate mofetil).
NB. Complete response is defined as proteinuria less than 0.5 g/day, with normal urinary sediment, a normal serum albumin concentration, and serum creatinine \<15% above the base-line value.
Female patients of child-bearing age and male patients agree to maintain effective birth control practice during the study.
You may not be if
Abnormal liver function tests
Hepatitis B surface antigen or hepatitis C antibody positive
Diabetic
Receiving NSAID or other agents known to influence urinary
Protein excretion
Allergic or intolerant to macrolide antibiotics or tacrolimus
