Life-threatening illness unrelated to cancer

Receiving other treatment (radiotherapy, antineoplastics or investigational agents) within protocol specified windows of first dose of TAK-441

Patients with brain metastases who do not meet criteria specified in study protocol

Known history of human immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C

Major surgery within 14 days before the first dose of TAK-441

Infection requiring systemic therapy, or other serious infection within 14 days of the first dose of TAK-441

Do not meet other clinical, laboratory or radiographic criteria as specified in the protocol

A Study of TAK-441 in Adult Patients With Advanced Nonhematologic Malignancies