Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy

Exclusion Criteria

• •10. History of any conditions that would prohibit testing contained in the NIH toolbox;
• •11. Non-English or non-Spanish speaking (to the extent that would limit the ability to complete study measures);
• •12. History of prior psychiatric illness requiring hospitalization;
• •13. Prior testosterone therapy;
• •14. History of or current or suspected hormonally dependent cancer , including carcinoma of the breast or prostate cancer;
• •15. Known hypersensitivity to any T gel ingredients including alcohol and soy products;
• •16. Hematocrit (HCT) greater than 55% (normal range in Colorado is up to 52) or transaminase elevation \>4x upper limit of the normal range.
• •17. Abnormal finding on digital rectal examination such as nodule, asymmetry, or induration (Does not include enlarged prostate or abnormal rectal tone)
• •18. PSA\>4.0
• •19. BMI \<16 or \>40kg/m2
• •20. History of untreated prolactinoma
• •21. History of severe heart failure or uncontrolled medical problem that would interfere with the participant's safety in the study as determined by the investigator.