Bipap Automatic Servo Ventilation (autoSV) Advanced in Central Apnea Patients

Inclusion Criteria

• •1. Males and females, ages 21-75.
• •2. Able and willing to provide written informed consent.
• •3. Diagnosis of Central Sleep Apnea such as Hunter Cheyne Stokes Breathing, Complex Sleep Apnea, or Central Apnea with current daily Opioid use or any other predominant central sleep apnea.
• •1. For participants diagnosed with Hunter Cheyne Stokes Breathing, at least 3 cycles of crescendo-decrescendo breathing amplitude AND either a Central Apnea Index (CAI) ≥ 5/hour OR the crescendo-decrescendo cycles last at least 10 consecutive minutes from an attended Diagnostic Polysomnogram (PSG).
• •2. For participants diagnosed with Central Sleep Apnea with current daily Opioid use or any other predominant central sleep apnea, an Apnea/Hypopnea Index (AHI) ≥ 15 and CAI \> 5 from an attended Diagnostic PSG.
• •3. For participants diagnosed with Complex Sleep Apnea, an AHI ≥ 15 and CAI \> 5 from a CPAP titration.
• •4. Systolic blood pressure \> 80 mm Hg at Visit 1.
• •5. Agreement to undergo a full-night, attended Diagnostic PSG.
• •6. Agreement to undergo a full-night, attended CPAP titration PSG.
• •7. Agreement to undergo a full-night, attended BiPAP automatic Servo Ventilation (autoSV) Advanced titration PSG