The specific aims of this study is to: (1) evaluate the antidepressant efficacy of rTMS on major depression; (2) evaluate the effects of rTMS on cognitive function in depressive patients; (3) assess the effects of rTMS on cerebral glucose metabolism in depressive patients as measured by 18FDG PET; (4) investigate the differences of the regional cerebral glucose uptake changes during rTMS between responders and nonresponders to rTMS.
Age
Any age
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Twenty patients fulfilling the diagnostic criteria of major depression according to DSM IV will be enrolled in the study.
Antidepressant medication will be maintained throughout the study period.
You may not be if
To exclude the effect of drug changes on post-rTMS cerebral glucose metabolism, the combinations and dosage of pre-rTMS antidepressant drugs will remain unchanged until the post-rTMS 18FDG PET is done.
Clareo Health | Repetitive Transcranial Magnetic Stimulation(rTMS) in the Treatment of Depression
