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Biology in Patients With Reflux Esophagitis | Clinical Trials | Clareo Health

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COMPLETEDNCT01194323

Biology in Patients With Reflux Esophagitis

GERD is a common condition in the western world. In most cases, the diagnostic is established by good response to empiric proton pump inhibitor (PPI) therapy. When the patient symptoms are refractory ...

Lead sponsor: Vanderbilt University Medical Center•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Vanderbilt University Medical Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Male or female
•Ages 18 years or older
•Undergoing EGD as standard of care at Vanderbilt's Digestive Diseases Center
•Esophageal erosion detected at EGD
•Abnormal pH monitoring
•Male or female
•Ages 18 years or older
•Undergoing EGD as standard of care at Vanderbilt's Digestive Diseases Center
•No complaints or history o heartburn or acid regurgitation
•No erosion at EGD
•Normal pH monitoring

Exclusion Criteria

•Less than 18 years of age
•Unable to provide informed consent
•Use of acid suppressive therapy within last 14 days
•known history of Barrett's esophagus, gastric surgery, alcoholism, significant motility condition
•contraindications to biopsy such as taking anticoagulants other than aspirin (coumadin, plavix) or allergies to local anesthetic

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 4, 2017Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment75

Start dateNov 2010

Last updatedApr 4, 2017

Condition

Locations shown

Vanderbilt University Digestive Diseases Center

Nashville, Tennessee

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 4, 2017Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions