TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery

Exclusion Criteria

• •Indication for emergency surgery
• •Known coagulopathy (as judged relevant by the investigator)
• •Known or suspected hypersensitivity to any ingredient of the investigational medicinal products (e.g. human fibrinogen, human thrombin and/or collagen of any origin)
• •Patient unwilling to receive blood products
• •Known current alcohol or drug abuse
• •Pregnancy, breastfeeding, no use of acceptable contraceptive method in females of childbearing potential
• •Dry surgical field of the targeted application area
• •Occurrence of any serious surgical complication
• •Disseminated intravascular coagulopathy (DIC), i.e. microvascular bleeding
• •Application of topical hemostatic material on the liver resection wound
• •Radiofrequency precoagulation of the liver resection wound except focal radiofrequency ablation of vessels as primary hemostatic treatment