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Keep this study
Lead
AdventHealth
With
University of Virginia
Covered self expandable metal stents (CSEMS) are three times larger in diameter than 10 Fr plastic stents. When compared to plastic stents, randomized trials have shown longer patency and fewer stent-related complications for CSEMS. The investigators hypothesize that placement of CSEMS would be a better treatment option for preoperative biliary decompression in patients with pancreatic cancer as there will be better drainage of the obstructed biliary system with fewer adverse events.
Age
19–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients with pancreatic cancer and mass in the head of pancreas causing jaundice.
Patients 19 yrs of age and older
Serum bilirubin \> 2mg/dl
CT: No evidence of distant metastasis or local vascular invasion (tumor surrounding portal or mesenteric vessels for more than 180 degrees of their circumference or an irregular vessel margin).
You may not be if
Karnofsky score \< 60
Prior (ERCP or PTC) attempts at biliary decompression for the same indication
Tumor-related gastric outlet obstruction (vomiting and oral intake of \< 1L/day)
Ongoing or planned neoadjuvant therapy
Cholangitis at presentation or coagulopathy needing reversal medication
Post-surgical anatomy
Multiple extra-hepatic biliary strictures or concomitant stricture in liver hilum
Failed ERCP's (Definition: Inability to deploy a biliary stent thereby requiring a PTC or surgery).
Clareo Health | Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression
