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Sexual Health on Antidepressants Through Physical Exercise | Clinical Trials | Clareo Health

COMPLETEDNA

Sexual Health on Antidepressants Through Physical Exercise

NCT01188720•University of Texas at Austin

Summary

Preliminary findings from a trial in the investigators laboratory suggest that acute exercise may ameliorate deficits in sexual arousal associated with use of antidepressants. The goal of this project is to evaluate the real-world effectiveness of an exercise-based intervention for these side effects in a community-based sample. The investigators hypothesize that general exercise will help improve sexual functioning in women taking antidepressants, and that exercise immediately before sexual activity - that is, acute exercise - will have an additional beneficial effect above and beyond that of general exercise.

Eligibility

Age

18 - No limit years

Sex

FEMALE

Healthy Volunteers

Inclusion Criteria

•female
•age 18 or older
•currently receiving a consistent dosage of escitalopram, citalopram, sertraline, desvenlafaxine, venlafaxine, or duloxetine
•currently sexually active
•willing and able to exercise
•experiencing regular menstrual cycles
•not currently pregnant and not intending to become pregnant during trial

Exclusion Criteria

•currently taking more than one psychoactive medication
•factors indicating risk of cardiovascular activity, including acute or chronic cardiovascular illness, including clinically significant hypertension (defined as self-reported hypertension or "blood pressure greater than 140/90" or receiving medications designed to treat hypertension); recent chest pain; frequent or recurrent faint or dizzy spells; severe or untreated exercise-related asthma; or musculoskeletal illness or injury that would be expected to worsen with physical exercise. Additionally, women will be excluded if they are found to have any of the following as measured during the fitness assessment of the first session: a BMI over 40, waist circumference over 40 inches, waist-to-hip ratio of greater than 0.9, systolic blood pressure greater than 150 or diastolic pressure over 95, or resting heart rate over 90.
•factors associated with significant genital nerve damage, including: previous major pelvic surgery that may have caused nerve damage, including hysterectomy, vulvectomy, circumcision, colostomy, cystostomy, or serious bladder, rectal, or abdominal surgery; or neurological impairment due to diabetes, stroke, pelvic nerve damage secondary to trauma, cancer treatments, myasthenia gravis, multiple sclerosis or spinal cord damage.
•factors associated with non-normative endocrine function, including: perimenopausal or menopausal status, or \>1 missed menstrual period in the previous 6 months; or currently pregnant, breastfeeding, or having breastfed within the past 3 months; or reporting clinically significant untreated renal or endocrine disease
•untreated serious mental health conditions
•sexual aversion or distress due to history of unwanted sexual contact

Locations (1)

University of Texas at Austin

Austin, Texas, United States

Key Dates

Start Date

November 1, 2010

Primary Completion Date

January 1, 2012

Completion Date

August 1, 2013

Last Updated

May 27, 2015

Enrollment

ACTUAL participants

Conditions

Sexual Dysfunction, PhysiologicalSexual Dysfunctions, Psychological

Interventions

Physical activity

BEHAVIORAL

Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women

NCT06308614

Sexual Dysfunction, Physiological

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COMPLETEDNA

Women's Interventions for Sexual Health: WISH

NCT05692960

Sexual Dysfunction, PhysiologicalBody Image+1 more

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COMPLETED

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 27, 2015Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Sexual Health on Antidepressants Through Physical Exercise

Inclusion Criteria

Exclusion Criteria

Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women

Women's Interventions for Sexual Health: WISH

Sexual Function Changes in High-Risk Pregnancies

Body Image and Sexuality After Bariatric Surgery

Evaluation of The Vaginal Renewal™ Program in Gynecologic Cancer Patients Experiencing Sexual Dysfunction

Bupropion in Sexual Dysfunction Among Methadone Maintenance Treatment Men