Lead Sponsor

Boehringer Ingelheim

Collaborators

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Diagnosis typ 2 diabetes mellitus
•Male and female on diet and exercise regimen, pre-treated with metformin 12 weeks prior to randomisation
•HbA1c equal or greater than 7.0% and less than or equal to 10% at visit 1
•18 years or more
•BMI equal or less than 45Kg/m2

•Uncontrolled hyperglycemia defined as glucose more that 13.3 mmol/L after overnight fast during placebo run-in
•Any other antidiabetic drug within 12 weeks prior to randomisation except metformin
•Acute coronary syndrome (non-STEMI, STEMI unstable angina pectoris), stroke or transient ischemic attack within 12 weeks of informed consent
•Indication of liver disease
•Moderate to severe renal impairment
•Bariatric surgery within past 2 years
•Medical history of cancer or treatment for cancer within last 5 years
•Blood dyscrasias or any disorders causing haemolysis or unstable red blood cell
•Contraindications hypersensitivity to concomitant drugs
•Treatment with anti-obesity drugs