Endoscopic Ultrasound-guided Celiac Plexus Neurolysis in the Management of Pain in Abdominal Non-pancreatic Malignancies

Inclusion Criteria

• •Diagnosis of an unresectable, non-pancreatic malignancy, including gastric, small intestinal, or proximal colonic malignancies, as well as malignancies of the liver and bile ducts (based on above celiac plexus innervations)
• •Pain directly related to the primary malignant process, as determined by the referring oncologist
• •Pain determined to be refractory to standard medical therapy, or when the medical therapy is ineffective due to certain limitations (such as severe constipation), as determined by the referring oncologist
• •Willingness to undergo EUS-guided CPN
• •Age \> 18 years
• •ECOG performance status of grades 0-3 \[7\]
• •The patient will need to sign informed consent prior to inclusion in this study