Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Pennsylvania
With
Hospira, now a wholly owned subsidiary of Pfizer
All patients enrolled in the study will be undergoing bronchoscopy, which is typically performed with sedation. All procedural sedation carries some risk. Several features of the study may lower the risk of sedation relative to that of conventional sedation. An anesthesiologist will be present throughout the procedure. Continuous monitoring of respiration with RIP will be employed. Administration of sedation will be via a volumetric syringe pump. Benefits specific to dexmedetomidine-ketamine include the lack of respiratory depression and greater hemodynamic stability.
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults over the age of 18 scheduled for elective flexible bronchoscopy in the endoscopy suite or OR of HUP
You may not be if
History of inability to complete bronchoscopy attributable to inadequate sedation
Requiring more than 2 LPM supplemental oxygen to maintain SaO2 \> 90%
History of allergy to study medications
Pregnancy
A history of psychosis
Any condition deemed likely by the pulmonologist or anesthesiologist to pose a significant risk due to elevation of blood pressure, including cerebral/aortic aneurysm, and or ischemic cardiovascular disease
Bradydysrhythmia deemed significant by the anesthesiologist or pulmonologist
A diagnosis of significant renal or hepatic impairment
