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Keep this study
Lead
Dallas VA Medical Center
The population for inclusion for this study will be drawn from the patients undergoing elective transabdominal colorectal surgery. This population was chosen due to its inherently high rate of superficial-incisional infection.Colorectal procedures stand out as a particularly highrisk surgery with respect to SSI. Several studies have reported rates of infection of 25% or more making colorectal surgeries an excellent opportunity for testing new strategies to reduce SSI.
This pilot project seeks to preliminarily evaluate two new strategies that are inexpensive and could be readily incorporated into current practice. The strategies are pressurized irrigation of the superficial surgical wound (above the fascia) and subcutaneous injection of gentamicin into the surgical wound prior to initial skin incision. Comparison will be made between prospectively enrolled patients and historic controls.The hypothesis to be tested is that these interventions will significantly reduce superficial incisional infection rates compared with historic control.
Age
18–95
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
VA patients getting transabdominal,elective colorectal procedures
willing and capable of giving self informed consent
You may not be if
patients unable to give informed consent
emergency colorectal procedures
transanal procedures
patients who have contaminated or dirty wounds that would preclude attempts at skin closure at the conclusion of the procedure
patients undergoing appendectomy
patients undergoing intraabdominal procedures not including surgical resection of the colon or rectum (ie.procedures involving small bowel , stomach)
patients with pre/op creatinine clearance less than 20ml/min
patients with known allergy or hypersensitivity to gentamicin
patients that have received gentamicin within 2 weeks of potential study date
Clareo Health | Effectiveness for Interventions to Minimize Surgical Site Infections