Oxidative Stress in Chronic Kidney Disease: Diet and Exercise

Exclusion Criteria

• •Any acute inflammatory condition (including chronic infection requiring treatment, and collagen vascular disease including active gout);
• •Pregnancy;
• •Taking high-dose anti-oxidants (Vitamin E or C);
• •Chronic use of anti-inflammatory medication except low dose (\< 10mg/d) prednisone and aspirin (\< 100 mg/day);
• •Significant cardiac or vascular disease (symptomatic disease or CV event including congestive heart failure within 6 months);
• •Significant occlusive atherosclerotic disease or ischemic disease (on non-invasive or invasive diagnostic procedures);
• •Significant physical immobility or disabilities (joint replacement, muscular disorders);
• •Type I diabetes mellitus, or Type II requiring insulin therapy;
• •History of poor adherence to medical regimen;
• •Those subjects who have a diagnosis of atrial fibrillation or a pacemaker will be allowed in the study but will not undergo Arterial Tonometry (PWV) studies.