Efficacy of L-carnitine Versus Placebo in the Treatment of Fatigue in Multiple Sclerosis

Exclusion Criteria

• •Patients with serious unstable disease :
• •* recurrent or serious relapses
• •* rapidly ongoing disability impairment in the preceding 6 months
• •* serious or non stabilized depression
• •Patients starting a new disease modifying therapy, immunosuppression or antidepressant therapy less than 3 months ago or not stabilized.
• •Patients with a treatment of fatigue or of other condition that may interfere with fatigue evaluation to the appreciation of the neurologist.
• •Energy drinks consumption or toxicomania.
• •All other reasons to the opinion of the neurologist that may impair study management, especially patient compliance, neuro-psychological disorders that may input questionnaires filling.
• •Person under protection of the law.
• •Participation in other clinical trials (allowing for exceptions, after recommendation from the scientific council).