Loading clinical trials...

Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache

Randomized, Placebo Controlled Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache

NCT01148303•Hartford Hospital

Summary

The investigators intend to study whether the use of the pain medication etoricoxib (Arcoxia) taken just before the Ramadan fast will prevent or lessen headache that some people get while fasting. The investigators hypothesize that etoricoxib will reduce the number of people getting headache, more than placebo. The investigators will do this by giving participants in the study either real medication or placebo (sugar pill) and comparing the results. The investigators will study this over two weeks. The first week one group will get the medicine and the other the placebo. The second the groups will switch. Neither the subjects nor the investigators will know who is in which group.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age 18 -65.
•Patients will be enrolled if they declared that they intended to complete the dawn to dusk Ramadan fast, and had demonstrated their commitment by doing so for the previous three years (unless medically prevented.)
•Patient states that he/she typically suffered from headache during fasting in the past.

Exclusion Criteria

•Patients with a history of severe cardiovascular disease, diabetes, asthma, COPD, hypertension, or a history of bleeding, particularly in the gastrointestinal tract
•Patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 (cyclooxygenase-2) inhibitors
•Pregnant or lactating patients. Sexually active women of childbearing age will be included only if using birth control
•Severe hepatic dysfunction
•Estimated renal creatinine clearance \<30 ml/min
•History of peptic ulcer, erosive gastritis, esophagitis or inflammatory bowel disease
•Congestive heart failure
•Patients with hypertension whose blood pressure is persistently elevated above 140/90mmHg and has not been adequately controlled Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
•Cancer or any other malignant disease
•History of medication overuse. Overuse of analgesics or antimigraine drugs according to the IHS criteria (chapter 8)

Locations (1)

Shaare Zedek Medical Center

Jerusalem, Israel

Key Dates

Start Date

July 1, 2010

Primary Completion Date

August 1, 2010

Completion Date

August 1, 2010

Last Updated

March 8, 2011

Enrollment

220

ACTUAL participants

Conditions

HeadacheFastingFasting HeadacheRamadan Headache

Interventions

Etoricoxib

DRUG

Etoricoxib

DRUG

Placebo

DRUG

Mind Body Balance for Pediatric Migraine

NCT04715685

HeadacheHeadache Disorders+6 more

View study

RECRUITINGNA

MyVitalC: Sleep and Everyday Headache Management

NCT07477236

SleepHeadaches

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 8, 2011Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache

Inclusion Criteria

Exclusion Criteria

Mind Body Balance for Pediatric Migraine

MyVitalC: Sleep and Everyday Headache Management

Light Exposure, Migraine Outcomes, and Sleep Quality

Effect of Isometric Neck Exercises on Cervicogenic Headache, Cortisol, and BDNF in Adolescents With Smartphone Addiction

Effectiveness of Third Occipital Nerve Pulsed Radiofrequency in Cervicogenic Headache

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)