Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Lantheus Biosciences Ltd.
Age
60–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Presence of MCI defined as abnormal cognition on objective testing in the absence of dementia or significant functional loss.
Absence of systemic or other neurological disease that may contribute to cognitive impairment or prevent follow-up over two years.
Able to give written informed consent.
Age \>/= 60 years of age
\>/= 7 years of education
You may not be if
Mini mental state examination (MMSE) score \< 24 at baseline
Clinical dementia rating (CDR) score \> 0.5 at baseline
Patients who receive regular medication of drugs which may adversely impact cognition (e.g. tricyclic antidepressants, antipsychotics and/or large doses of hypnotics or anxiolytics)
Existing or history of cancer
History of severe head trauma, brain surgery or intracranial hematoma with permanent brain lesion
Lifetime history of major affective disorder, schizophrenia, or schizo-affective disorder
Contraindications to MRI (Magnetic resonance imaging)
Relevant history, physical or imaging findings of neurological disease other than MCI and mild depression
History of severe anaphylactic reaction or high risk of allergic reaction to drugs
Patient has received another investigational drug in the preceding 14 days
