Saves the questions and what to expect into your notes, next to the visit they belong to.
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Lead
University of Monastir
Patients presenting to the emergency department with exacerbation of COPD are randomized to receive nebulised ipratropuim bromide or combined nebulised and an intravenous bolus of magnesium sulfate during 1 hour.
Age
40–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
40 years old or over
have known or suspected COPD based on pulmonary function test, arterial blood gas, clinical history, physical examination, and chest radiograph
worsening of dyspnea within 2 weeks,
partial pressure of arterial carbon dioxide (PaCO2) \>45 mmHg
respiratory rate \>24/min
arterial pH \<7.35
partial pressure of arterial oxygen (PaO2) \<50 mmHg under room air
You may not be if
hypersensitivity to anticholinergics and to magnesium sulfate
patients that received anticholinergics within 6 hours before ED admission
systolic arterial pressure \<90 mmHg or need to vasoactive drugs
Clareo Health | Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease