Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo

Inclusion Criteria

• •Normal, healthy male and female children and adult
• •Written and verbal informed consent must be obtained. Patients age 12 to 17 (inclusive) must sign an assent for the study and a parent or a legal guardian must sign the informed consent.
• •Women of child-bearing potential must be non-pregnant and non-nursing, and must be willing to avoid pregnancy during the course of the study and during the menstrual cycle following completion of their participation in the study.
• •Able to refrain from the use of all other topical acne medications or antibiotics during the treatment period.
• •Considered reliable and capable of understanding their responsibility and role in the study.