Helicobacter Pylori Eradication to Prevent Gastric Cancer

Exclusion Criteria

• •Severe concomitant illness (eg, severe hypertension, coronary heart disease, diabetes mellitus, stroke, asthma, liver cirrhosis, tuberculosis, infectious hepatitis, and cardiac, respiratory, hepatic, or renal insufficiency)
• •Patients with epilepsy or severe mental illness
• •Previous diagnosis of cancer
• •A history of esophageal or gastric surgery
• •Drug abuse and drug dependence
• •Allergic to omeprazole, amoxicillin, or clarithromycin
• •Pregnant and lactating women
• •Previous history of H pylori eradication treatment
• •A negative 13C-urea breath test (UBT)
• •A definite indication of H. pylori eradication (eg, gastric or duodenum ulcer)
• •Dysplasia or carcinoma lesions are found in esophageal or gastric histopathological examination
• •Other factors or conditions might influence the results of study