Role of Inflammation in Progressive Multifocal Leukoencephalopathy (PML)

Exclusion Criteria

• •1. Presence of opportunistic brain lesions other than PML. ( e.g., toxoplasmosis, lymphoma)
• •2. Presence of confounding neurological disorder such as brain neoplasm etc.
• •In addition patients with a contraindication to MRI examination will be excluded from study. Contraindications to the MRI examination include:
• •1. Medically unstable or hematological, renal, or hepatic dysfunction.
• •2. Cardiac pacemaker
• •3. Internal clips,
• •4. Metal implants, or external clips with 10 mm of the head.
• •5. Metal in the eyes.
• •6. Pregnant
• •7. Claustrophobia