Participant has basilar or hemiplegic migraine headache

Participant has taken medication for acute headache on more than 15 days per month in the 3 months prior to screening

Participant is taking prophylactic medication for migraine and daily dose has changed within 4 weeks prior to screening

Participant has history of significant liver disease

Participant has had cardiac surgery or symptoms within 3 months of screening

Participant has confounding pain syndromes, psychiatric conditions, dementia, or major neurological disorders other than migraine

Participant has history of neoplastic disease ≤ 5 years prior to signing informed consent

Participant has history of gastric or small intestinal surgery

Participant consumes 3 or more alcoholic drinks per day

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)