Patients who have had a respiratory tract infection within 4 weeks prior to Visit 1

Patients with concomitant pulmonary disease

Patients with a history of asthma

Any patient with lung cancer or a history of lung cancer

Patients with a history of certain cardiovascular co-morbid conditions

Patients with a known history and diagnosis of alpha-1 antitrypsin deficiency

Patients in the active phase of a supervised pulmonary rehabilitation program

Patients contraindicated for inhaled anticholinergic agents and β2 agonists

A Study to Assess the Long-term Safety of QVA149