Major surgery (including joint surgery) within 12 weeks prior to baseline or planned major surgery within 6 months after baseline.

History of or current inflammatory joint disease other than rheumatoid arthritis (RA).

Treatment with a biologic agent at any time prior to baseline.

Intra-articular or parenteral corticosteroids ≤ 4 weeks prior to baseline.

Active current infection or history of recurrent bacterial, viral, fungal or mycobacterial infection.

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis