Presence of active renal disease

Previous intolerance or hypersensibility to any of the active components

Active infection

Unmeasurable levels of TMPT

Pregnancy

Presence of a severe flare that requires other immunosuppressive treatment for its control

Any Psychiatric or social condition that did not ensure the patient´s follow-up and patient´s collaboration

Previous treatment with EC-MPS or Azathioprine in the last 2 months

Previous treatment with biological therapy in the last 3 months for anti-TNF therapy or in the last year for anti-CD20 therapy

ALT or GPT \>120 UI/mL non-lupus related in the last 30 days

Leucopenia \<1000x10E6 non-lupus related in the last 30 days

Symptoms related to other medical conditions non-lupus related such as antiphospholipid syndrome.

Enteric-coated Mycophenolate Sodium Versus Azathioprine for the Extra-renal Lupus Manifestations