Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Inclusion Criteria

• •Subjects will be selected for this protocol based on either a clinical diagnosis of non-medullary thyroid cancer and the presence of one family member with the disease or the presence of 2 living family members with this disease. Patient selection for this protocol will not be based on gender, race, or ethnic background.
• •In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• •Adults or minor (\>= 7 years+), males and females.
• •An unaffected individual with (Bullet) 2 first-degree relatives who have or have had nonmedullary thyroid cancer
• •OR
• •An affected individual with documented diagnosis of non-medullary thyroid cancer and (Bullet) one living relative with documented non-medullary thyroid cancer (Note: as this is a familial study, subjects do not need to present with the disease)
• •OR
• •Any member of an affected family. (Note: for this study, an affected family is defined as a family having 2 or more 1st degree relatives with a documented diagnosis of FNMTC.)
• •Adults must be able to understand and the willingness to sign the informed consent document.
• •Adults must be able to complete the family history questionnaire.