Personal or family history of epilepsy, brain tumor, brain injury

History of metallic particles in the eye or head outside the mouth

Cardiac pacemakers, implanted neurostimulators, cochlear implants, implanted medication pumps

History of drug or alcohol abuse

Pregnancy

Relapse of MS \< 30 days prior to inclusion

I.v. corticosteroid treatment \< 30 days prior to inclusion

Change of immunomodulatory therapy \< 30 days prior to inclusion

Change of antidepressant therapy \< 3 months prior to inclusion

Comedication with neuroleptics and tricyclic antidepressants (amitriptyline etc.) during the entire study

patients with increased intracranial pressure (which lowers seizure threshold)

intracardiac lines

significant heart disease

bipolar disorder

history of stroke or other brain lesions

Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis