Lead Sponsor

University of Utah

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

•Males (18 - 65) and postmenopausal females (up to age 65) with metabolic syndrome who have stage 1 hypertension.
•Since all subjects will have Stage 1 hypertension, they must also meet at least 2 of the following criteria of metabolic syndrome to qualify for the study; waist circumference of \>35 inches for women or \>40 inches in men, fasting plasma triglycerides of \>150 mg/dl, fasting glucose of \>100 mg/dl, HDL of \<40 in men. Pre-hypertension or greater (130 + mm Hg systolic/80+mm Hg diastolic) is defined by the 7th Report for the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.

•Subjects who are allergic to tea or grapes (on which the supplement is based).
•Participants who have blood pressure less than 130 mmHg / 80 mmHg,
•have a history of a prior cardiovascular event, diabetes, pregnancy, liver disease, renal insufficiency, any chronic disease that might interfere with study participation,
•BMI above 40 kg/m2,
•consumption of \>12 alcoholic drinks weekly,
•unwillingness to stop current supplement intake or use of calcium/ magnesium antacids.