Extension Study to Assess Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis

Exclusion Criteria

• •Inability or unwillingness to undergo repeated subcutaneous injections
• •Inability to comply with study or follow-up procedures
• •Any medical or psychiatric condition which, in the investigator's opinion would preclude the participant from adhering to the protocol or completing the study per protocol
• •Pregnant or nursing (lactating) women, where pregnancy is defined as the state of a female after conception and until the termination of gestation, confirmed by a positive hCG laboratory test (\> 5 mIU/mL)
• •Women of childbearing potential (WoCBP), defined as all women physiologically capable of becoming pregnant, UNLESS
• •They are using simultaneously double barrier or two acceptable methods of contraception
• •They are postmenopausal with an appropriate clinical profile and had no regular menstrual bleeding for at least twelve (12) months prior to initial dosing
• •They have undergone reliable surgical sterilization at least six (6) months prior to initial dosing
• •Their career, lifestyle, or sexual orientation precludes intercourse with a male partner
• •Partners have been sterilized by vasectomy or other reliable means